Research Papers: General

Investigating femtosecond-laser-induced two-photon photoacoustic generation

[+] Author Affiliations
Ben E. Urban, Ji Yi, Hao F. Zhang

Northwestern University, Department of Biomedical Engineering, Evanston, Illinois 60208, United States

Vladislav Yakovlev

Texas A&M University, Department of Biomedical Engineering, College Station, Texas 77843, United States

J. Biomed. Opt. 19(8), 085001 (Aug 01, 2014). doi:10.1117/1.JBO.19.8.085001
History: Received March 7, 2014; Revised May 30, 2014; Accepted July 7, 2014
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Abstract.  We investigated two-photon absorption-based photoacoustic generation and compared it with corresponding photoluminescence emission. Experimental results revealed expected quadratic dependences on the incident optical fluence in both photoacoustic and photoluminescence processes. We also investigated the influence of optical scattering on the generation of two-photon photoacoustic and photoluminescence signals and found that photoacoustic signals attenuated more slowly than photoluminescence signals when the optical scattering coefficient was increased, which was attributed to a weaker ultrasonic attenuation than that the optical attenuation in the scattering medium. Finally, we showed three-dimensional two-photon photoacoustic imaging.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Ben E. Urban ; Ji Yi ; Vladislav Yakovlev and Hao F. Zhang
"Investigating femtosecond-laser-induced two-photon photoacoustic generation", J. Biomed. Opt. 19(8), 085001 (Aug 01, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.8.085001


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