Research Papers: Imaging

Graphics processing unit-based quantitative second-harmonic generation imaging

[+] Author Affiliations
Mohammad Mahfuzul Kabir

University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Laboratory for Photonics Research of Bio/nano Environments (PROBE), Urbana, Illinois 61801, United States

ASM Jonayat

University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Urbana, Illinois 61801, United States

Sanjay Patel

University of Illinois at Urbana-Champaign, Department of Electrical and Computer Engineering, Urbana, Illinois 61801, United States

Kimani C. Toussaint, Jr.

University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Laboratory for Photonics Research of Bio/nano Environments (PROBE), Urbana, Illinois 61801, United States

University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Urbana, Illinois 61801, United States

University of Illinois at Urbana-Champaign, Affiliate in the Department of Electrical and Computer Engineering, and Bioengineering, Urbana, Illinois 61801, United States

J. Biomed. Opt. 19(9), 096009 (Sep 15, 2014). doi:10.1117/1.JBO.19.9.096009
History: Received June 4, 2014; Revised August 7, 2014; Accepted August 15, 2014
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Abstract.  We adapt a graphics processing unit (GPU) to dynamic quantitative second-harmonic generation imaging. We demonstrate the temporal advantage of the GPU-based approach by computing the number of frames analyzed per second from SHG image videos showing varying fiber orientations. In comparison to our previously reported CPU-based approach, our GPU-based image analysis results in 10× improvement in computational time. This work can be adapted to other quantitative, nonlinear imaging techniques and provides a significant step toward obtaining quantitative information from fast in vivo biological processes.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Mohammad Mahfuzul Kabir ; ASM Jonayat ; Sanjay Patel and Kimani C. Toussaint, Jr.
"Graphics processing unit-based quantitative second-harmonic generation imaging", J. Biomed. Opt. 19(9), 096009 (Sep 15, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.9.096009


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