Research Papers: Imaging

Consecutively reconstructing absorption and scattering distributions in turbid media with multiple-illumination photoacoustic tomography

[+] Author Affiliations
Peng Shao

University of Alberta, Department of Electrical and Computer Engineering, 9107-116 Street, Edmonton T6G 2V4, Canada

Tyler J. Harrison

University of Alberta, Department of Electrical and Computer Engineering, 9107-116 Street, Edmonton T6G 2V4, Canada

Roger J. Zemp

University of Alberta, Department of Electrical and Computer Engineering, 9107-116 Street, Edmonton T6G 2V4, Canada

J. Biomed. Opt. 19(12), 126009 (Dec 17, 2014). doi:10.1117/1.JBO.19.12.126009
History: Received March 20, 2014; Accepted November 5, 2014
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Abstract.  We propose a theoretical framework for consecutively reconstructing absorption and scattering distributions in turbid soft tissue in an iterative manner. This approach takes advantage of the stability of a recently reported least-squares fixed-point iterative method for reconstructing an optical absorption coefficient map to iteratively update estimates of absorption and scattering for each iteration. Simulations demonstrate that this method converges to an accurate estimate of the optical properties within only a small number of iterations and is robust to noise at realistic signal-to-noise levels.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Peng Shao ; Tyler J. Harrison and Roger J. Zemp
"Consecutively reconstructing absorption and scattering distributions in turbid media with multiple-illumination photoacoustic tomography", J. Biomed. Opt. 19(12), 126009 (Dec 17, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.12.126009


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