Research Papers: Sensing

Objective characterization of bruise evolution using photothermal depth profiling and Monte Carlo modeling

[+] Author Affiliations
Luka Vidovič

Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia

Matija Milanič

Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia

Boris Majaron

Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia

J. Biomed. Opt. 20(1), 017001 (Jan 02, 2015). doi:10.1117/1.JBO.20.1.017001
History: Received July 4, 2014; Accepted December 1, 2014
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Abstract.  Pulsed photothermal radiometry (PPTR) allows noninvasive determination of laser-induced temperature depth profiles in optically scattering layered structures. The obtained profiles provide information on spatial distribution of selected chromophores such as melanin and hemoglobin in human skin. We apply the described approach to study time evolution of incidental bruises (hematomas) in human subjects. By combining numerical simulations of laser energy deposition in bruised skin with objective fitting of the predicted and measured PPTR signals, we can quantitatively characterize the key processes involved in bruise evolution (i.e., hemoglobin mass diffusion and biochemical decomposition). Simultaneous analysis of PPTR signals obtained at various times post injury provides an insight into the variations of these parameters during the bruise healing process. The presented methodology and results advance our understanding of the bruise evolution and represent an important step toward development of an objective technique for age determination of traumatic bruises in forensic medicine.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Luka Vidovič ; Matija Milanič and Boris Majaron
"Objective characterization of bruise evolution using photothermal depth profiling and Monte Carlo modeling", J. Biomed. Opt. 20(1), 017001 (Jan 02, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.1.017001


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