Since the first appearance of near infrared (NIR) femtosecond lasers in refractive surgery as a tool for flap creation,1 the number of applications for these lasers in ophthalmic surgery has grown significantly. It is now possible to complete at least myopic correction using only the femtosecond laser,2,3 although this procedure still has not made pulsed ultraviolet (UV) lasers obsolete. The excimer laser has been the laser source of choice for photorefractive keratectomy (PRK) since the introduction of the procedure;4,5 later on, it also took a choice position in laser-assisted in situ keratomileusis (LASIK)-type surgeries. Excimer laser-based systems evolved from high energy, low repetition rate lasers that covered a large area of the cornea in a single shot into repetition rate flying spot machines with sophisticated scanning patterns and fast eye tracking systems.6–9 Most practical disadvantages of the excimer lasers (intense maintenance required, toxic gases used as gain medium, relatively low stability of output, poor beam quality) have been successfully overcome or at least became manageable by the use of sophisticated engineering solutions and application protocols.10,11 The clinical outcomes of UV systems for corneal ablation based upon nanosecond solid-state lasers with harmonic generators12,13 have been demonstrated to be equivalent to those of excimer lasers.14 However, the inherent advantages of solid-state lasers like better shot-to-shot stability did not prove to be decisive in gaining a considerable market share. This situation could change if solid-state technology would allow for significant integration of the equipment used for both stages of the LASIK treatment, thus reducing the cost of the systems.15,16 In this regard, the use of high power femtosecond lasers capable of producing substantial UV power via harmonic generation appears a straightforward solution.