Research Papers: Imaging

Cherenkov luminescence imaging in transparent media and the imaging of thin or shallow sources

[+] Author Affiliations
Sergey Komarov, Dong Zhou, Yongjian Liu, Yuan-Chuan Tai

Washington University in St. Louis, Department of Radiology, 510 S. Kingshighway Boulevard, Campus Box 8225, St. Louis, Missouri 63110, United States

J. Biomed. Opt. 20(3), 036011 (Mar 19, 2015). doi:10.1117/1.JBO.20.3.036011
History: Received December 15, 2014; Accepted February 25, 2015
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Abstract.  In this work, we demonstrated the possibility of high spatial resolution Cherenkov luminescence imaging (CLI) for objects in transparent media. We also demonstrated the possibility of the CLI of thin opaque objects using optical transducers. Results demonstrate that submillimeter resolution CLI is achievable for beta-emitting radionuclides, including Br76 that emits positrons of very high energy. The imaging of beta-emitters through scintillation detectors exhibits lower resolution when compared to CLI of the same sources. The application of optical transducers for the CLI was demonstrated using plants labeled with CO112 and phantoms containing beta-emitters.

© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Sergey Komarov ; Dong Zhou ; Yongjian Liu and Yuan-Chuan Tai
"Cherenkov luminescence imaging in transparent media and the imaging of thin or shallow sources", J. Biomed. Opt. 20(3), 036011 (Mar 19, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.3.036011


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