Research Papers: General

Research on the change of complex refractive index of porcine muscle during natural dehydration

[+] Author Affiliations
Zhichao Deng, Jin Wang, Yuanze Liu, Qing Ye, Tengqian Sun, Wenyuan Zhou, Chunping Zhang, Jianguo Tian

Nankai University, School of Physics and TEDA Applied Physics School, Ministry of Education, Key Laboratory of Weak-Light Nonlinear Photonics, Tianjin 300071, China

Jianchun Mei

Nankai University, Advanced Technology Institute, Tianjin 300071, China

J. Biomed. Opt. 20(4), 045001 (Apr 13, 2015). doi:10.1117/1.JBO.20.4.045001
History: Received January 27, 2015; Accepted March 20, 2015
Text Size: A A A

Abstract.  The physical changes of tissue are complicated to evaluate during optical clearing (OC) treatment. Monitoring the changes of optical parameters, including the complex refractive index (CRI), helps people better understand the OC process. From the imaginary part of CRI, we can deduce the extinction coefficient of tissue. Based on the total internal reflection method, the time-dependent CRI of porcine muscle during natural dehydration is well determined. Results show that the real RI increases continuously with the increase of dehydration time, whereas the extinction coefficient initially increases and then decreases. Finally, the extinction coefficient becomes much smaller than the initial value, which demonstrates that better tissue optical clarity is obtained. The change tendency of the extinction coefficient of tissue is used to qualitatively explain the dynamic change of transmittance of a natural dehydrated tissue. Consequently, CRI, especially its imaginary part, is a very useful optical parameter by which to evaluate the OC effect.

Figures in this Article
© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Zhichao Deng ; Jin Wang ; Yuanze Liu ; Qing Ye ; Tengqian Sun, et al.
"Research on the change of complex refractive index of porcine muscle during natural dehydration", J. Biomed. Opt. 20(4), 045001 (Apr 13, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.4.045001


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.