Research Papers: Imaging

Use of functional near-infrared spectroscopy to evaluate the effects of anodal transcranial direct current stimulation on brain connectivity in motor-related cortex

[+] Author Affiliations
Jiaqing Yan, Yun Wei

Yanshan University, Institute of Electrical Engineering, No. 438, Hebei Street, Haigang District, Qinhuangdao 066004, China

Yinghua Wang, Gang Xu, Zheng Li, Xiaoli Li

Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, No. 19, XinJieKouWai Street, HaiDian District, Beijing 100875, China

Beijing Normal University, Center for Collaboration and Innovation in Brain and Learning Sciences, No. 19, XinJieKouWai Street, HaiDian District, Beijing 100875, China

J. Biomed. Opt. 20(4), 046007 (Apr 20, 2015). doi:10.1117/1.JBO.20.4.046007
History: Received February 10, 2015; Accepted March 25, 2015
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Abstract.  Transcranial direct current stimulation (tDCS) is a noninvasive, safe and convenient neuro-modulatory technique in neurological rehabilitation, treatment, and other aspects of brain disorders. However, evaluating the effects of tDCS is still difficult. We aimed to evaluate the effects of tDCS using hemodynamic changes using functional near-infrared spectroscopy (fNIRS). Five healthy participants were employed and anodal tDCS was applied to the left motor-related cortex, with cathodes positioned on the right dorsolateral supraorbital area. fNIRS data were collected from the right motor-related area at the same time. Functional connectivity (FC) between intracortical regions was calculated between fNIRS channels using a minimum variance distortion-less response magnitude squared coherence (MVDR-MSC) method. The levels of Oxy-HbO change and the FC between channels during the prestimulation, stimulation, and poststimulation stages were compared. Results showed no significant level difference, but the FC measured by MVDR-MSC significantly decreased during tDCS compared with pre-tDCS and post-tDCS, although the FC difference between pre-tDCS and post-tDCS was not significant. We conclude that coherence calculated from resting state fNIRS may be a useful tool for evaluating the effects of anodal tDCS and optimizing parameters for tDCS application.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Jiaqing Yan ; Yun Wei ; Yinghua Wang ; Gang Xu ; Zheng Li, et al.
"Use of functional near-infrared spectroscopy to evaluate the effects of anodal transcranial direct current stimulation on brain connectivity in motor-related cortex", J. Biomed. Opt. 20(4), 046007 (Apr 20, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.4.046007


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