Research Papers: Imaging

Influence of multiple scattering and absorption on the full scattering profile and the isobaric point in tissue

[+] Author Affiliations
Hamootal Duadi, Dror Fixler

Bar Ilan University, Institute of Nanotechnology and Advanced Materials, Faculty of Engineering, Ramat Gan 5290002, Israel

J. Biomed. Opt. 20(5), 056010 (May 27, 2015). doi:10.1117/1.JBO.20.5.056010
History: Received March 11, 2015; Accepted April 27, 2015
Text Size: A A A

Abstract.  Light reflectance and transmission from soft tissue has been utilized in noninvasive clinical measurement devices such as the photoplethysmograph (PPG) and reflectance pulse oximeter. Incident light on the skin travels into the underlying layers and is in part reflected back to the surface, in part transferred and in part absorbed. Most methods of near infrared (NIR) spectroscopy focus on the volume reflectance from a semi-infinite sample, while very few measure transmission. We have previously shown that examining the full scattering profile (angular distribution of exiting photons) provides more comprehensive information when measuring from a cylindrical tissue. Furthermore, an isobaric point was found which is not dependent on changes in the reduced scattering coefficient. The angle corresponding to this isobaric point depends on the tissue diameter. We investigated the role of multiple scattering and absorption on the full scattering profile of a cylindrical tissue. First, we define the range in which multiple scattering occurs for different tissue diameters. Next, we examine the role of the absorption coefficient in the attenuation of the full scattering profile. We demonstrate that the absorption linearly influences the intensity at each angle of the full scattering profile and, more importantly, the absorption does not change the position of the isobaric point. The findings of this work demonstrate a realistic model for optical tissue measurements such as NIR spectroscopy, PPG, and pulse oximetery.

Figures in this Article
© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Hamootal Duadi and Dror Fixler
"Influence of multiple scattering and absorption on the full scattering profile and the isobaric point in tissue", J. Biomed. Opt. 20(5), 056010 (May 27, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.5.056010


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.