Research Papers: Therapeutic

Diagnosis of breast tumor using thermal tomography q−r curve

[+] Author Affiliations
Guilian Shi

Wuhan University, School of Physics and Technology, Department of Electronic Science and Technology, No. 299, Bayi Road, Wuchang District, Wuhan City, Hubei Province 430072, China

Hubei University of Science and Technology, School of Biomedical Engineering, No. 88, Xianning Road, Xianning City, Hubei Province 437100, China

Lin Wang, Fei Han, Chengwen Liang, Kaiyang Li

Wuhan University, School of Physics and Technology, Department of Electronic Science and Technology, No. 299, Bayi Road, Wuchang District, Wuhan City, Hubei Province 430072, China

J. Biomed. Opt. 20(6), 068001 (Jun 24, 2015). doi:10.1117/1.JBO.20.6.068001
History: Received December 9, 2014; Accepted May 28, 2015
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Abstract.  Metabolic heat, the product following the metabolism of cells, is closely related to the pathological information of living organisms, which means there are strong connections between the heat distribution and the pathological state of the living organism. The mathematical function δ is introduced in the classical Pennes bioheat transfer equation as a point heat source, and by simplifying the boundary condition, a bioheat transfer model is established. Based on the temperature distribution of the human body surface, the qr curve of heat intensity q varying with depth r is acquired while combining the fitting method of the Lorentz curve. According to 34,977 clinical confirmed cases and the corresponding classified statistics, diagnostic criteria (for breast diseases) for judging diseases by the qr curve are proposed. The P-value of our statistics is <0.05, which means our classified statistics are reliable. Six typical clinical examinations are performed, and the diagnosis results are very consistent with those of B-ultrasonic images, molybdenum target x-ray, and pathological examination, which suggests that the method of diagnosing diseases with a qr curve has very good prospects for application. It is radiation free and noninvasive to the human body.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Guilian Shi ; Lin Wang ; Fei Han ; Chengwen Liang and Kaiyang Li
"Diagnosis of breast tumor using thermal tomography q−r curve", J. Biomed. Opt. 20(6), 068001 (Jun 24, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.6.068001


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