Research Papers: General

Contrast improvement of continuous wave diffuse optical tomography reconstruction by hybrid approach using least square and genetic algorithm

[+] Author Affiliations
Rusha Patra, Pranab K. Dutta

Indian Institute of Technology Kharagpur, Department of Electrical Engineering, Kharagpur, West Bengal 721302, India

J. Biomed. Opt. 20(7), 075009 (Jul 29, 2015). doi:10.1117/1.JBO.20.7.075009
History: Received January 30, 2015; Accepted June 29, 2015
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Abstract.  Reconstruction of the absorption coefficient of tissue with good contrast is of key importance in functional diffuse optical imaging. A hybrid approach using model-based iterative image reconstruction and a genetic algorithm is proposed to enhance the contrast of the reconstructed image. The proposed method yields an observed contrast of 98.4%, mean square error of 0.638×103, and object centroid error of (0.001 to 0.22) mm. Experimental validation of the proposed method has also been provided with tissue-like phantoms which shows a significant improvement in image quality and thus establishes the potential of the method for functional diffuse optical tomography reconstruction with continuous wave setup. A case study of finger joint imaging is illustrated as well to show the prospect of the proposed method in clinical diagnosis. The method can also be applied to the concentration measurement of a region of interest in a turbid medium.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Rusha Patra and Pranab K. Dutta
"Contrast improvement of continuous wave diffuse optical tomography reconstruction by hybrid approach using least square and genetic algorithm", J. Biomed. Opt. 20(7), 075009 (Jul 29, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.7.075009


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