Research Papers: General

Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy

[+] Author Affiliations
Maciej S. Wróbel, Malgorzata Jędrzejewska-Szczerska, Stanislaw Galla

Gdańsk University of Technology, Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Narutowicza 11/12, Gdańsk 80-233, Poland

Leszek Piechowski, Miroslaw Sawczak, Adam Cenian

Polish Academy of Sciences, The Szewalski Institute of Fluid-flow Machinery, Physical Aspects of Ecoenergy Department, Fiszera 14, Gdańsk 80-952, Poland

Alexey P. Popov, Alexander V. Bykov

University of Oulu, Faculty of Information Technology and Electrical Engineering, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 Oulu, Finland

Tomsk State University, 36 Lenina Avenue, Tomsk 634050, Russia

Valery V. Tuchin

University of Oulu, Faculty of Information Technology and Electrical Engineering, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 Oulu, Finland

Tomsk State University, 36 Lenina Avenue, Tomsk 634050, Russia

Saratov State University, Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya, Saratov 410012, Russia

Russian Academy of Sciences, Institute of Precise Mechanics and Control, 24 Rabochaya, Saratov 410028, Russia

J. Biomed. Opt. 20(8), 085003 (Aug 11, 2015). doi:10.1117/1.JBO.20.8.085003
History: Received March 13, 2015; Accepted July 1, 2015
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Abstract.  Skin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to thermal conductivity and capacitance); thus, they can be used as substitutes for human skin for approximate evaluation of laser heating efficiency in an almost real environment. Thermographic imaging was applied to measure the spatial and temporal temperature distributions on the surface of laser-irradiated phantoms. The study yielded results of heating with regard to phantom thickness and absorption, as well as laser settings. The methodology developed can be used in practice for preclinical evaluations of laser treatment for dermatology.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Maciej S. Wróbel ; Malgorzata Jędrzejewska-Szczerska ; Stanislaw Galla ; Leszek Piechowski ; Miroslaw Sawczak, et al.
"Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy", J. Biomed. Opt. 20(8), 085003 (Aug 11, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.8.085003


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