Research Papers: Therapeutic

Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: a randomized, controlled trial

[+] Author Affiliations
Juliana Cassol Spanemberg, Maria Antonia Zancanaro de Figueiredo, Karen Cherubini, Fernanda Gonçalves Salum

Pontifical Catholic University of Rio Grande do Sul–PUCRS, Oral Medicine Division, Avenida Ipiranga 6690, room 231, CEP 90610-000, Porto Alegre, Brazil

José López López

University of Barcelona: Bellvitge University Campus, Oral Pathology Division, Departament of Odontoestomatology-School of Dentistry, Pabellón de Gobierno C/FeixaLLarga, s/n, 08907 L’Hospitalet de Llobregat, Barcelona, Spain

J. Biomed. Opt. 20(9), 098001 (Sep 11, 2015). doi:10.1117/1.JBO.20.9.098001
History: Received February 25, 2015; Accepted August 14, 2015
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Abstract.  The aim of the present study was to assess the effect of low-level laser therapy (LLLT) in the treatment of burning mouth syndrome (BMS). A diode laser was used in 78 BMS patients who were randomly assigned into four groups: IR1W, n=20 (830 nm, 100 mW, 5 J, 176J/cm2, 50 s, LLLT weekly sessions, 10 sessions); IR3W, n=20 (830 nm, 100 mW, 5 J, 176J/cm2, 50 s, three LLLT weekly sessions, 9 sessions); red laser, n=19 (685 nm, 35 mW, 2 J, 72J/cm2, 58 s, three LLLT weekly sessions, 9 sessions); and control-group (CG), n=19. Symptoms were assessed at the end of the treatment and eight weeks later; quality of life related to oral health was assessed using the Oral Health Impact Profile (OHIP-14). Statistical analysis was carried out using repeated measures analysis of variance followed by the posthoc Tukey test. There was significant reduction of the symptoms in all groups at the end of the treatment, which was maintained in the follow-up. The scores of the IR1W and IR3W laser groups differed significantly from those of the CG. There was also a decrease in the OHIP-14 scores in the four groups. The IR3W laser group scores differed significantly from those of the CG. LLLT reduces the symptoms of BMS and may be an alternative therapeutic strategy for the relief of symptoms in patients with BMS.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Juliana Cassol Spanemberg ; José López López ; Maria Antonia Zancanaro de Figueiredo ; Karen Cherubini and Fernanda Gonçalves Salum
"Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: a randomized, controlled trial", J. Biomed. Opt. 20(9), 098001 (Sep 11, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.9.098001


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