Research Papers: General

Reflectance near-infrared measurements for determining changes in skin barrier function and scattering in relation to moisturizer application

[+] Author Affiliations
Meha Qassem, Panayiotis A. Kyriacou

City University London, Biomedical Engineering Research Centre, Northampton Square, London EC1V 0HB, United Kingdom

J. Biomed. Opt. 20(9), 095008 (Sep 16, 2015). doi:10.1117/1.JBO.20.9.095008
History: Received February 18, 2015; Accepted August 21, 2015
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Abstract.  Skin moisture relates to the state of multiple skin constituents and aspects, but unfortunately, a device which could provide comprehensive and in vivo analysis is not available. Nevertheless, several reports have demonstrated accurate estimations of dermal water content using near-infrared spectroscopy (NIRS), and the potential of employing this technique in skin analysis. We aim to investigate whether NIRS could detect changes in skin barrier function through evaluation of skin water uptake in relation to moisturizer application. NIR and capacitance data were collected from 20 volunteers at both forearms, prior to and after seven days of regular moisturizer use. Results indicated lower peak intensities at the 1940-nm minima and higher intensities at the 1450-nm equivalent minima with moisturizer abstinence, while the opposite was true with regular moisturizer application. As the light beam would have traveled deeper into the skin at 1450 nm, it has been concluded that long-term, frequent moisturizer use had limited the penetration of extrinsic water. Partial least squares analysis showed that separation of sample’s scores increased with abstinence of moisturizer use. Thus, NIRS can provide valuable information not only on dermal water contents but also on additional parameters such as skin barrier function.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Meha Qassem and Panayiotis A. Kyriacou
"Reflectance near-infrared measurements for determining changes in skin barrier function and scattering in relation to moisturizer application", J. Biomed. Opt. 20(9), 095008 (Sep 16, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.9.095008


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