Research Papers: General

Selection of voxel size and photon number in voxel-based Monte Carlo method: criteria and applications

[+] Author Affiliations
Dong Li, Bin Chen, Wei Yu Ran, Wen Juan Wu

Xi’an Jiaotong University, State Key Laboratory of Multiphase Flow in Power Engineering, Xi’an 710049, China

Guo Xiang Wang

Xi’an Jiaotong University, State Key Laboratory of Multiphase Flow in Power Engineering, Xi’an 710049, China

University of Akron, Department of Mechanical Engineering, Akron, Ohio 44325-3903, United States

J. Biomed. Opt. 20(9), 095014 (Sep 29, 2015). doi:10.1117/1.JBO.20.9.095014
History: Received May 13, 2015; Accepted August 31, 2015
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Abstract.  The voxel-based Monte Carlo method (VMC) is now a gold standard in the simulation of light propagation in turbid media. For complex tissue structures, however, the computational cost will be higher when small voxels are used to improve smoothness of tissue interface and a large number of photons are used to obtain accurate results. To reduce computational cost, criteria were proposed to determine the voxel size and photon number in 3-dimensional VMC simulations with acceptable accuracy and computation time. The selection of the voxel size can be expressed as a function of tissue geometry and optical properties. The photon number should be at least 5 times the total voxel number. These criteria are further applied in developing a photon ray splitting scheme of local grid refinement technique to reduce computational cost of a nonuniform tissue structure with significantly varying optical properties. In the proposed technique, a nonuniform refined grid system is used, where fine grids are used for the tissue with high absorption and complex geometry, and coarse grids are used for the other part. In this technique, the total photon number is selected based on the voxel size of the coarse grid. Furthermore, the photon-splitting scheme is developed to satisfy the statistical accuracy requirement for the dense grid area. Result shows that local grid refinement technique photon ray splitting scheme can accelerate the computation by 7.6 times (reduce time consumption from 17.5 to 2.3 h) in the simulation of laser light energy deposition in skin tissue that contains port wine stain lesions.

© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Dong Li ; Bin Chen ; Wei Yu Ran ; Guo Xiang Wang and Wen Juan Wu
"Selection of voxel size and photon number in voxel-based Monte Carlo method: criteria and applications", J. Biomed. Opt. 20(9), 095014 (Sep 29, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.9.095014


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