JBO Letters

Imaging autofluorescence temporal signatures of the human ocular fundus in vivo

[+] Author Affiliations
Asael Papour, Oscar Stafsudd

University of California, Los Angeles, Electrical Engineering Department, 56-125B Engineering, IV Building, 420 Westwood Plaza, Los Angeles, California 90095-1594, United States

Zachary Taylor, Warren Grundfest

University of California, Los Angeles, Department of Bioengineering, 410 Westwood Plaza, Room 5121, Engineering V, P.O. Box 951600, Los Angeles, California 90095-1600, United States

Irena Tsui

University of California, Los Angeles, Stein Eye Institute and Doheny Eye Institute, 100 Stein Plaza, Los Angeles, California 90095-7000, United States

J. Biomed. Opt. 20(11), 110505 (Nov 23, 2015). doi:10.1117/1.JBO.20.11.110505
History: Received March 20, 2015; Accepted October 22, 2015
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Abstract.  We demonstrate real-time in vivo fundus imaging capabilities of our fluorescence lifetime imaging technology for the first time. This implementation of lifetime imaging uses light emitting diodes to capture full-field images capable of showing direct tissue contrast without executing curve fitting or lifetime calculations. Preliminary results of fundus images are presented, investigating autofluorescence imaging potential of various retina biomarkers for early detection of macular diseases.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Asael Papour ; Zachary Taylor ; Oscar Stafsudd ; Irena Tsui and Warren Grundfest
"Imaging autofluorescence temporal signatures of the human ocular fundus in vivo", J. Biomed. Opt. 20(11), 110505 (Nov 23, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.11.110505


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