Research Papers: Therapeutic

Temperature-controlled laser-soldering system and its clinical application for bonding skin incisions

[+] Author Affiliations
David Simhon, Ilan Gabay, Tamar Vasilyev, Abraham Katzir

Tel Aviv University, School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv 69978, Israel

Gregory Shpolyansky, Moshe Hashmonai

Israel Institute of Technology, Faculty of Medicine, Technion, Haifa 32000, Israel

Israel Nur, Roberto Meidler

Omrix Biopharmaceuticals Ltd., R&D Department, Nes-Ziona 76106, Israel

Ossama Abu Hatoum

Ha’Emek Medical Center, Department of Surgery B, Afula 18101, Israel

Doron Kopelman

Israel Institute of Technology, Faculty of Medicine, Technion, Haifa 32000, Israel

Ha’Emek Medical Center, Department of Surgery B, Afula 18101, Israel

J. Biomed. Opt. 20(12), 128002 (Dec 18, 2015). doi:10.1117/1.JBO.20.12.128002
History: Received July 5, 2015; Accepted November 17, 2015
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Abstract.  Laser tissue soldering is a method of repairing incisions. It involves the application of a biological solder to the approximated edges of the incision and heating it with a laser beam. A pilot clinical study was carried out on 10 patients who underwent laparoscopic cholecystectomy. Of the four abdominal incisions in each patient, two were sutured and two were laser soldered. Cicatrization, esthetical appearance, degree of pain, and pruritus in the incisions were examined on postoperative days 1, 7, and 30. The soldered wounds were watertight and healed well, with no discharge from these wounds or infection. The total closure time was equal in both methods, but the net soldering time was much shorter than suturing. There was no difference between the two types of wound closure with respect to the pain and pruritus on a follow-up of one month. Esthetically, the soldered incisions were estimated as good as the sutured ones. The present study confirmed that temperature-controlled laser soldering of human skin incisions is clinically feasible, and the results obtained were at least equivalent to those of standard suturing.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

David Simhon ; Ilan Gabay ; Gregory Shpolyansky ; Tamar Vasilyev ; Israel Nur, et al.
"Temperature-controlled laser-soldering system and its clinical application for bonding skin incisions", J. Biomed. Opt. 20(12), 128002 (Dec 18, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.12.128002


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