We investigate and assess the utility of a simple scheme for continuous absolute blood flow monitoring based on diffuse correlation spectroscopy (DCS). The scheme calibrates DCS using venous-occlusion diffuse optical spectroscopy (VO-DOS) measurements of arm muscle tissue at a single time-point. A calibration coefficient () for the arm is determined, permitting conversion of DCS blood flow indices to absolute blood flow units, and a study of healthy adults () is carried out to ascertain the variability of . The average DCS calibration coefficient for the right (i.e., dominant) arm was . However, variability can be significant and is apparent in our site-to-site and day-to-day repeated measurements. The peak hyperemic blood flow overshoot relative to baseline resting flow was also studied following arm-cuff ischemia; excellent agreement between VO-DOS and DCS was found (, , ). Finally, we show that incorporation of subject-specific absolute optical properties significantly improves blood flow calibration accuracy.