Research Papers: Therapeutic

Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing

[+] Author Affiliations
Elina A. Genina, Alexey N. Bashkatov

National Research Saratov State University, Optics and Biophotonics Department, 83 Astrakhanskaya Street, Saratov 410012, Russia

National Research Tomsk State University, Interdisciplinary Laboratory of Biophotonics, 36 Lenin Avenue, Tomsk 634050, Russia

Vladimir A. Titorenko

Saratov State Medical University, Dental Faculty, 112 Bolshaya Kazachaya Street, Saratov 410012, Russia

Andrey V. Belikov

St. Petersburg National Research University of Information Technologies, Mechanics, and Optics, Laser Technologies and Laser Technique Department, 49 Kronverkskiy Avenue, Saint-Petersburg 197101, Russia

Valery V. Tuchin

National Research Saratov State University, Optics and Biophotonics Department, 83 Astrakhanskaya Street, Saratov 410012, Russia

National Research Tomsk State University, Interdisciplinary Laboratory of Biophotonics, 36 Lenin Avenue, Tomsk 634050, Russia

Institute of Precise Mechanics and Control of RAS, 24 Rabochaya Street, Saratov 410028, Russia

J. Biomed. Opt. 20(12), 128004 (Dec 29, 2015). doi:10.1117/1.JBO.20.12.128004
History: Received September 29, 2015; Accepted November 19, 2015
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Abstract.  The efficacy of blue light-emitting toothbrushes (B-LETBs) (405 to 420 nm, power density 2  mW/cm2) for reduction of dental plaques and gingival inflammation has been evaluated. Microbiological study has shown the multifactor therapeutic action of the B-LETBs on oral pathological microflora: in addition to partial mechanical removal of bacteria, photodynamic action suppresses them up to 97.5%. In the pilot clinical studies, subjects with mild to moderate gingivitis have been randomly divided into two groups: a treatment group that used the B-LETBs and a control group that used standard toothbrushes. Indices of plaque, gingival bleeding, and inflammation have been evaluated. A significant improvement of all dental indices in comparison with the baseline (by 59%, 66%, and 82% for plaque, gingival bleeding, and inflammation, respectively) has been found. The treatment group has demonstrated up to 50% improvement relative to the control group. We have proposed the B-LETBs to serve for prevention of gingivitis or as an alternative to conventional antibiotic treatment of this disease due to their effectiveness and the absence of drug side effects and bacterial resistance.

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© 2015 Society of Photo-Optical Instrumentation Engineers

Citation

Elina A. Genina ; Vladimir A. Titorenko ; Andrey V. Belikov ; Alexey N. Bashkatov and Valery V. Tuchin
"Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing", J. Biomed. Opt. 20(12), 128004 (Dec 29, 2015). ; http://dx.doi.org/10.1117/1.JBO.20.12.128004


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