Research Papers: Imaging

Contrast enhancement in microscopy of human thyroid tumors by means of acousto-optic adaptive spatial filtering

[+] Author Affiliations
Konstantin B. Yushkov, Vladimir Y. Molchanov

National University of Science and Technology “MISiS,” 4 Leninsky Prospekt, Moscow 119049, Russia

Pavel V. Belousov

Lomonosov Moscow State University, Faculty of Biology, 1 Leninskie Gory, Moscow 119991, Russia

Aleksander Y. Abrosimov

National University of Science and Technology “MISiS,” 4 Leninsky Prospekt, Moscow 119049, Russia

Pathology Department, Federal State Institution “Endocrinology Research Center,” 11 Dm. Ulyanova Street, Moscow 117036, Russia

J. Biomed. Opt. 21(1), 016003 (Jan 12, 2016). doi:10.1117/1.JBO.21.1.016003
History: Received August 23, 2015; Accepted December 14, 2015
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Abstract.  We report a method for edge enhancement in the images of transparent samples using analog image processing in coherent light. The experimental technique is based on adaptive spatial filtering with an acousto-optic tunable filter in a telecentric optical system. We demonstrate processing of microscopic images of unstained and stained histological sections of human thyroid tumor with improved contrast.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Konstantin B. Yushkov ; Vladimir Y. Molchanov ; Pavel V. Belousov and Aleksander Y. Abrosimov
"Contrast enhancement in microscopy of human thyroid tumors by means of acousto-optic adaptive spatial filtering", J. Biomed. Opt. 21(1), 016003 (Jan 12, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.1.016003


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