Special Section on Selected Topics in Biophotonics: Photoacoustic Tomography and Fiber-Based Lasers and Supercontinuum Sources

Noninvasively measuring oxygen saturation of human finger-joint vessels by multi-transducer functional photoacoustic tomography

[+] Author Affiliations
Zijian Deng, Changhui Li

Peking University, Department of Biomedical Engineering, College of Engineering, No. 5 Yiheyuan Road, Haidian, Beijing 100871, China

J. Biomed. Opt. 21(6), 061009 (May 12, 2016). doi:10.1117/1.JBO.21.6.061009
History: Received November 6, 2015; Accepted April 19, 2016
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Abstract.  Imaging small blood vessels and measuring their functional information in finger joint are still challenges for clinical imaging modalities. In this study, we developed a multi-transducer functional photoacoustic tomography (PAT) system and successfully imaged human finger-joint vessels from 1  mm to <0.2  mm in diameter. In addition, the oxygen saturation (SO2) values of these vessels were also measured. Our results demonstrate that PAT can provide both anatomical and functional information of individual finger-joint vessels with different sizes, which might help the study of finger-joint diseases, such as rheumatoid arthritis.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Zijian Deng and Changhui Li
"Noninvasively measuring oxygen saturation of human finger-joint vessels by multi-transducer functional photoacoustic tomography", J. Biomed. Opt. 21(6), 061009 (May 12, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.6.061009


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