Research Papers: Imaging

Fast direct reconstruction strategy of dynamic fluorescence molecular tomography using graphics processing units

[+] Author Affiliations
Maomao Chen, Jiulou Zhang, Chuangjian Cai, Yang Gao, Jianwen Luo

Tsinghua University, School of Medicine, Department of Biomedical Engineering, Beijing 100084, China

J. Biomed. Opt. 21(6), 066010 (Jun 14, 2016). doi:10.1117/1.JBO.21.6.066010
History: Received March 17, 2016; Accepted May 23, 2016
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Abstract.  Dynamic fluorescence molecular tomography (DFMT) is a valuable method to evaluate the metabolic process of contrast agents in different organs in vivo, and direct reconstruction methods can improve the temporal resolution of DFMT. However, challenges still remain due to the large time consumption of the direct reconstruction methods. An acceleration strategy using graphics processing units (GPU) is presented. The procedure of conjugate gradient optimization in the direct reconstruction method is programmed using the compute unified device architecture and then accelerated on GPU. Numerical simulations and in vivo experiments are performed to validate the feasibility of the strategy. The results demonstrate that, compared with the traditional method, the proposed strategy can reduce the time consumption by 90% without a degradation of quality.

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Citation

Maomao Chen ; Jiulou Zhang ; Chuangjian Cai ; Yang Gao and Jianwen Luo
"Fast direct reconstruction strategy of dynamic fluorescence molecular tomography using graphics processing units", J. Biomed. Opt. 21(6), 066010 (Jun 14, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.6.066010


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