Research Papers: General

Fabrication of various optical tissue phantoms by the spin-coating method

[+] Author Affiliations
Jihoon Park, Myungjin Ha, Sungkon Yu, Byungjo Jung

Yonsei University, Department of Biomedical Engineering, 1 Yonseidae-gil, Wonju, Gangwon-do 220-710, Republic of Korea

J. Biomed. Opt. 21(6), 065008 (Jun 29, 2016). doi:10.1117/1.JBO.21.6.065008
History: Received December 19, 2015; Accepted June 13, 2016
Text Size: A A A

Abstract.  Although numerous studies have been performed to fabricate various optical tissue phantom (OTP) models, the fabrication of OTPs that simulate skin layers is laborious and time-consuming owing to the intricate characteristics of skin tissue. This study presents various OTP models that optically and structurally simulate the epidermis–dermis skin layer. The spin-coating method was employed to reproduce a uniform thin layer that mimics the epidermis layer, and the fabrication parameters were optimized for epoxy and silicone reference materials. Various OTP models simulating blood vessels and hyperpigmentation lesions were fabricated using the two reference materials to determine their feasibility. The suitability of each of the two reference materials for OTP fabrication was qualitatively evaluated by comparing the quality of the OTP models.

Figures in this Article
© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Jihoon Park ; Myungjin Ha ; Sungkon Yu and Byungjo Jung
"Fabrication of various optical tissue phantoms by the spin-coating method", J. Biomed. Opt. 21(6), 065008 (Jun 29, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.6.065008


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.