Special Section on Polarized Light for Biomedical Applications

Backscattering of linearly polarized light from turbid tissue-like scattering medium with rough surface

[+] Author Affiliations
Alexander Doronin

Yale University, Department of Computer Science, Computer Graphics Group, New Haven 06511, United States

Lioudmila Tchvialeva, Igor Markhvida

University of British Columbia and Vancouver Coastal Health Research Institute, Department of Dermatology and Skin Science, Photomedicine Institute, Vancouver V5Z 4E8, Canada

Tim K. Lee

University of British Columbia and Vancouver Coastal Health Research Institute, Department of Dermatology and Skin Science, Photomedicine Institute, Vancouver V5Z 4E8, Canada

BC Cancer Agency, Departments of Cancer Control Research and Integrative Oncology, Vancouver V5Z 1L3, Canada

Simon Fraser University, School of Computing Science, Burnaby V5A 1S6, Canada

Igor Meglinski

University of Oulu, Opto-Electronics and Measurement Techniques Laboratory, Oulu FI-9014, Finland

J. Biomed. Opt. 21(7), 071117 (Jul 11, 2016). doi:10.1117/1.JBO.21.7.071117
History: Received December 23, 2014; Accepted June 14, 2016
Text Size: A A A

Abstract.  In the framework of further development of a unified computational tool for the needs of biomedical optics, we introduce an electric field Monte Carlo (MC) model for simulation of backscattering of coherent linearly polarized light from a turbid tissue-like scattering medium with a rough surface. We consider the laser speckle patterns formation and the role of surface roughness in the depolarization of linearly polarized light backscattered from the medium. The mutual phase shifts due to the photons’ pathlength difference within the medium and due to reflection/refraction on the rough surface of the medium are taken into account. The validation of the model includes the creation of the phantoms of various roughness and optical properties, measurements of co- and cross-polarized components of the backscattered/reflected light, its analysis and extensive computer modeling accelerated by parallel computing on the NVIDIA graphics processing units using compute unified device architecture (CUDA). The analysis of the spatial intensity distribution is based on second-order statistics that shows a strong correlation with the surface roughness, both with the results of modeling and experiment. The results of modeling show a good agreement with the results of experimental measurements on phantoms mimicking human skin. The developed MC approach can be used for the direct simulation of light scattered by the turbid scattering medium with various roughness of the surface.

Figures in this Article
© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Alexander Doronin ; Lioudmila Tchvialeva ; Igor Markhvida ; Tim K. Lee and Igor Meglinski
"Backscattering of linearly polarized light from turbid tissue-like scattering medium with rough surface", J. Biomed. Opt. 21(7), 071117 (Jul 11, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.7.071117


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.