Research Papers: General

Automated cervical precancerous cells screening system based on Fourier transform infrared spectroscopy features

[+] Author Affiliations
Yessi Jusman

University of Malaya, Department of Biomedical Engineering, Faculty of Engineering, 50603 Kuala Lumpur, Malaysia

Universitas Abdurrab, Department of Informatics Engineering, Faculty of Engineering, Pekanbaru, 28291 Riau, Indonesia

Nor Ashidi Mat Isa

University of Science Malaysia, School of Electrical and Electronic Engineering, Engineering Campus, Nibong Tebal, 14300 Penang, Malaysia

Siew-Cheok Ng, Khairunnisa Hasikin, Noor Azuan Abu Osman

University of Malaya, Department of Biomedical Engineering, Faculty of Engineering, 50603 Kuala Lumpur, Malaysia

J. Biomed. Opt. 21(7), 075005 (Jul 11, 2016). doi:10.1117/1.JBO.21.7.075005
History: Received December 28, 2015; Accepted June 15, 2016
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Abstract.  Fourier transform infrared (FTIR) spectroscopy technique can detect the abnormality of a cervical cell that occurs before the morphological change could be observed under the light microscope as employed in conventional techniques. This paper presents developed features extraction for an automated screening system for cervical precancerous cell based on the FTIR spectroscopy as a second opinion to pathologists. The automated system generally consists of the developed features extraction and classification stages. Signal processing techniques are used in the features extraction stage. Then, discriminant analysis and principal component analysis are employed to select dominant features for the classification process. The datasets of the cervical precancerous cells obtained from the feature selection process are classified using a hybrid multilayered perceptron network. The proposed system achieved 92% accuracy.

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Citation

Yessi Jusman ; Nor Ashidi Mat Isa ; Siew-Cheok Ng ; Khairunnisa Hasikin and Noor Azuan Abu Osman
"Automated cervical precancerous cells screening system based on Fourier transform infrared spectroscopy features", J. Biomed. Opt. 21(7), 075005 (Jul 11, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.7.075005


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