Research Papers: Imaging

High-temporal-resolution, full-field optical angiography based on short-time modulation depth for vascular occlusion tests

[+] Author Affiliations
Riwei Liao

Foshan University, Department of Photoelectric Technology, Foshan 528000, China

South China Normal University, School of Physics and Telecommunication, Guangzhou 510006, China

Mingyi Wang, Dingan Han, Yaguang Zeng

Foshan University, Department of Photoelectric Technology, Foshan 528000, China

Zuohua Huang

South China Normal University, School of Physics and Telecommunication, Guangzhou 510006, China

J. Biomed. Opt. 21(8), 086002 (Aug 04, 2016). doi:10.1117/1.JBO.21.8.086002
History: Received January 25, 2016; Accepted July 19, 2016
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Abstract.  We developed high-temporal-resolution, full-field optical angiography for use in vascular occlusion tests (VOTs). In the proposed method, undersampled signals are acquired by a high-speed digital camera that separates the dynamic and static speckle signals. The two types of speckle signal are used to calculate the short-time modulation depth (STMD) of each of the camera pixels. STMD is then used to realize high-temporal-resolution, full-field optical angiography. Phantom and biological experiments conducted and demonstrated the feasibility of using our proposed method to perform VOTs and to study the reaction kinetics in microfluidic systems.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Riwei Liao ; Mingyi Wang ; Dingan Han ; Zuohua Huang and Yaguang Zeng
"High-temporal-resolution, full-field optical angiography based on short-time modulation depth for vascular occlusion tests", J. Biomed. Opt. 21(8), 086002 (Aug 04, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.8.086002


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