Research Papers: Imaging

Angular compounding by full-channel B-scan modulation encoding for optical coherence tomography speckle reduction

[+] Author Affiliations
Pei Li, Liping Zhou, Yang Ni, Zhihua Ding, Peng Li

Zhejiang University, College of Optical Science and Engineering, State Key Lab of Modern Optical Instrumentation, Hangzhou, Zhejiang 310027, China

J. Biomed. Opt. 21(8), 086014 (Aug 24, 2016). doi:10.1117/1.JBO.21.8.086014
History: Received April 26, 2016; Accepted August 10, 2016
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Abstract.  We describe an angular compounding method by full-channel B-scan modulation encoding for speckle reduction in optical coherence tomography. The complex-valued spectral interferogram (SI) is reconstructed by removing one of the conjugate terms in the depth space. Fourier transform of the complex SI along the lateral direction enables a full-channel (with both negative and positive Fourier space) for B-scan modulation in the spatial frequency (ν) domain. A full-size probe beam, determined by the scanning mirror size, is centered on the mirror pivot, which allows the negative and positive half-channels working in parallel. Compared with the existing method, where only a half-channel (negative or positive) works alone, the proposed full-channel method offers more than twice the performance in speckle reduction. The feasibility of the proposed full-space approach is validated through both the phantom and in vivo human thumbnail experiments.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Pei Li ; Liping Zhou ; Yang Ni ; Zhihua Ding and Peng Li
"Angular compounding by full-channel B-scan modulation encoding for optical coherence tomography speckle reduction", J. Biomed. Opt. 21(8), 086014 (Aug 24, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.8.086014


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