JBO Letters

Lorentz force optical coherence elastography

[+] Author Affiliations
Chen Wu, Manmohan Singh, Zhaolong Han, Raksha Raghunathan, Chih-Hao Liu, Jiasong Li, Alexander Schill

University of Houston, Department of Biomedical Engineering, 3605 Cullen Boulevard, Houston, Texas 77204, United States

Kirill V. Larin

University of Houston, Department of Biomedical Engineering, 3605 Cullen Boulevard, Houston, Texas 77204, United States

Tomsk State University, Interdisciplinary Laboratory of Biophotonics, 36 Lenin Avenue, Tomsk 634050, Russia

Baylor College of Medicine, Molecular Physiology and Biophysics, One Baylor Plaza, Houston, Texas 77030, United States

J. Biomed. Opt. 21(9), 090502 (Sep 12, 2016). doi:10.1117/1.JBO.21.9.090502
History: Received June 25, 2016; Accepted August 16, 2016
Text Size: A A A

Abstract.  Quantifying tissue biomechanical properties can assist in detection of abnormalities and monitoring disease progression and/or response to a therapy. Optical coherence elastography (OCE) has emerged as a promising technique for noninvasively characterizing tissue biomechanical properties. Several mechanical loading techniques have been proposed to induce static or transient deformations in tissues, but each has its own areas of applications and limitations. This study demonstrates the combination of Lorentz force excitation and phase-sensitive OCE at 1.5  million A-lines per second to quantify the elasticity of tissue by directly imaging Lorentz force-induced elastic waves. This method of tissue excitation opens the possibility of a wide range of investigations using tissue biocurrents and conductivity for biomechanical analysis.

Figures in this Article
© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Chen Wu ; Manmohan Singh ; Zhaolong Han ; Raksha Raghunathan ; Chih-Hao Liu, et al.
"Lorentz force optical coherence elastography", J. Biomed. Opt. 21(9), 090502 (Sep 12, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.9.090502


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.