Research Papers: Sensing

Study of transmittance and reflectance spectra of the cornea and the sclera in the THz frequency range

[+] Author Affiliations
Elena N. Iomdina, Alisa A. Sianosyan

Moscow Helmholtz Research Institute of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya Street, Moscow 105062, Russia

Gregory N. Goltsman

Moscow State Pedagogical University, Department of Physics, 29 Malaya Pirogovskaya Street, Moscow 119435, Russia

National Research University Higher School of Economics, Moscow Institute of Electronics and Mathematics, 34 Tallinskaya Street, Moscow 123458, Russia

Sergey V. Seliverstov, Kseniya O. Teplyakova, Anastasia A. Rusova

Moscow State Pedagogical University, Department of Physics, 29 Malaya Pirogovskaya Street, Moscow 119435, Russia

J. Biomed. Opt. 21(9), 097002 (Sep 14, 2016). doi:10.1117/1.JBO.21.9.097002
History: Received April 16, 2016; Accepted August 26, 2016
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Abstract.  An adequate water balance (hydration extent) is one of the basic factors of normal eye function, including its external shells: the cornea and the sclera. Adequate control of corneal and scleral hydration is very important for early diagnosis of a variety of eye diseases, stating indications for and contraindications against keratorefractive surgeries and the choice of contact lens correction solutions. THz systems of creating images in reflected beams are likely to become ideal instruments of noninvasive control of corneal and scleral hydration degrees. This paper reports on the results of a study involving transmittance and reflectance spectra for the cornea and the sclera of rabbit and human eyes, as well as those of the rabbit eye, in the frequency range of 0.13 to 0.32 THz. The dependence of the reflectance coefficient of these tissues on water mass percentage content was determined. The experiments were performed on three corneas, three rabbit scleras, two rabbit eyes, and three human scleras. The preliminary results demonstrate that the proposed technique, based on the use of a continuous THz radiation, may be utilized to create a device for noninvasive control of corneal and scleral hydration, which has clear potential of broad practical application.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Elena N. Iomdina ; Gregory N. Goltsman ; Sergey V. Seliverstov ; Alisa A. Sianosyan ; Kseniya O. Teplyakova, et al.
"Study of transmittance and reflectance spectra of the cornea and the sclera in the THz frequency range", J. Biomed. Opt. 21(9), 097002 (Sep 14, 2016). ; http://dx.doi.org/10.1117/1.JBO.21.9.097002


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