Research Papers: General

Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 1: theory

[+] Author Affiliations
Payman Rajai, Rejean Munger

University of Ottawa, Physics Department, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada

Henry Schriemer

University of Ottawa, Physics Department, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada

University of Ottawa, School of Electrical Engineering and Computer Science, Ottawa, Ontario K1N 6N5, Canada

Ahmad Amjadi

Sharif University of Technology, Physics Department, P.O. Box: 11155-9161, Tehran, Iran

J. Biomed. Opt. 22(1), 015002 (Jan 28, 2017). doi:10.1117/1.JBO.22.1.015002
History: Received October 17, 2016; Accepted January 3, 2017
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Abstract.  We introduce a theoretical framework for simultaneous refractive index and thickness measurement of multilayer systems using the Fourier domain optical coherence tomography (FD-OCT) system without any previous information about the item under investigation. The input data to the new formalism are the FD-OCT measured optical path lengths and properly selected spectral components of the FD-OCT interference spectrum. No additional arrangement, reference reflector, or mechanical scanning is needed in this approach. Simulation results show that the accuracy of the extracted parameters depends on the index contrast of the sample while it is insensitive to the sample’s thickness profile. For transparent biological samples with smooth interfaces, when the object is in an aqueous medium and has indices <1.55, this method can extract indices and thicknesses with the absolute error 0.001.

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© 2017 Society of Photo-Optical Instrumentation Engineers

Citation

Payman Rajai ; Henry Schriemer ; Ahmad Amjadi and Rejean Munger
"Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 1: theory", J. Biomed. Opt. 22(1), 015002 (Jan 28, 2017). ; http://dx.doi.org/10.1117/1.JBO.22.1.015002


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