Research Papers: General

Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 2: implementation

[+] Author Affiliations
Payman Rajai, Rejean Munger

University of Ottawa, Physics Department, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada

Henry Schriemer

University of Ottawa, Physics Department, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada

University of Ottawa, School of Electrical Engineering and Computer Science, 25 Templeton Avenue, Ottawa, Ontario K1N 6N5, Canada

Ahmad Amjadi

Sharif University of Technology, Physics Department, P.O. Box 11155-9161, Tehran, Iran

J. Biomed. Opt. 22(1), 015003 (Feb 02, 2017). doi:10.1117/1.JBO.22.1.015003
History: Received October 17, 2016; Accepted January 3, 2017
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Abstract.  We introduce a theoretical method for simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography (FD-OCT) without any auxiliary arrangement. The input data to the formalism are the FD-OCT measured optical path lengths (OPLs) and properly selected spectral components of FD-OCT interference spectrum. The outputs of the formalism can be affected significantly by uncertainty in measuring the OPLs. An optimization method is introduced to deal with the relatively large amount of uncertainty in measured OPLs and enhance the final results. Simulation result shows that by using the optimization method, indices can be extracted with the absolute error 0.001 for transparent biological samples having indices <1.55.

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© 2017 Society of Photo-Optical Instrumentation Engineers

Citation

Payman Rajai ; Henry Schriemer ; Ahmad Amjadi and Rejean Munger
"Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 2: implementation", J. Biomed. Opt. 22(1), 015003 (Feb 02, 2017). ; http://dx.doi.org/10.1117/1.JBO.22.1.015003


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