To conclude this subsection, our multimodal setup enables simultaneous imaging of the propagation of a mechanical wave using FF-OCT and the propagation of a calcium wave using fluorescence. Due to the simultaneous nature of the measurements, we demonstrate that the mechanical waves propagating in the sample are linked with biological activity in the tissue, i.e., the calcium wave, which is known to cause fiber contraction.37 It is particularly critical here in an ex vivo tissue to acquire both pieces of information at the same time. Indeed, since the tissue is altered, its activity can be rapidly decreasing. Therefore, with a sequential acquisition multimodal system, by the time a movie was captured with one modality, the activity may have stopped before switching to the other. Also, as we are looking for waves, switching between modalities from one frame to the next would significantly lower the acquisition speed, meaning the wave propagation might be undetectable.