Special Section on Advanced Laser Technologies for Biophotonics

Photoacoustic imaging probe for detecting lymph nodes and spreading of cancer at various depths

[+] Author Affiliations
Yong-Jae Lee

Electronics and Telecommunications Research Institute, Diagnostic Device Research Section, Daejeon, Republic of Korea

Chungnam National University, Department of Physics, Daejeon, Republic of Korea

Eun-Ju Jeong, Hyun-Woo Song, Chang-Geun Ahn, Hyung Wook Noh, Joo Yong Sim, Dong Hoon Song, Bong Kyu Kim

Electronics and Telecommunications Research Institute, Diagnostic Device Research Section, Daejeon, Republic of Korea

Min Yong Jeon

Chungnam National University, Department of Physics, Daejeon, Republic of Korea

Susung Lee, Heewon Kim

Alpinion Medical System Co., Ltd., Probe Development Team, Seoul, Republic of Korea

Meihua Zhang

Seoul National University Hospital, Radiology of Breast Care Center, Seoul, Republic of Korea

J. Biomed. Opt. 22(9), 091513 (Apr 25, 2017). doi:10.1117/1.JBO.22.9.091513
History: Received December 2, 2016; Accepted April 5, 2017
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Abstract.  We propose a compact and easy to use photoacoustic imaging (PAI) probe structure using a single strand of optical fiber and a beam combiner doubly reflecting acoustic waves for convenient detection of lymph nodes and cancers. Conventional PAI probes have difficulty detecting lymph nodes just beneath the skin or simultaneously investigating lymph nodes located in shallow as well as deep regions from skin without any supplementary material because the light and acoustic beams are intersecting obliquely in the probe. To overcome the limitations and improve their convenience, we propose a probe structure in which the illuminated light beam axis coincides with the axis of the ultrasound. The developed PAI probe was able to simultaneously achieve a wide range of images positioned from shallow to deep regions without the use of any supplementary material. Moreover, the proposed probe had low transmission losses for the light and acoustic beams. Therefore, the proposed PAI probe will be useful to easily detect lymph nodes and cancers in real clinical fields.

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© 2017 Society of Photo-Optical Instrumentation Engineers

Citation

Yong-Jae Lee ; Eun-Ju Jeong ; Hyun-Woo Song ; Chang-Geun Ahn ; Hyung Wook Noh, et al.
"Photoacoustic imaging probe for detecting lymph nodes and spreading of cancer at various depths", J. Biomed. Opt. 22(9), 091513 (Apr 25, 2017). ; http://dx.doi.org/10.1117/1.JBO.22.9.091513


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