Research Papers: Imaging

Direct numerical simulation of the initial stage of a thermally induced microcavitation in a water-rich biotissue triggered by a nanosecond pulsed laser

[+] Author Affiliations
Sy-Bor Wen, Kevin Ly, Arun Bhaskar

Texas A&M University, Mechanical Engineering, College Station, Texas, United States

Morgan S. Schmidt

711th Human Effectiveness Directorate, Airman Systems Directorate, Bioeffects Division, Radio Frequency Bioeffects Branch, Joint Base San Antonio, Fort Sam Houston, Texas, United States

Robert J. Thomas

711th Human Effectiveness Directorate, Airman Systems Directorate, Bioeffects Division, Optical Radiation Bioeffects Branch, Joint Base San Antonio, Fort Sam Houston, Texas, United States

J. Biomed. Opt. 22(5), 056002 (May 03, 2017). doi:10.1117/1.JBO.22.5.056002
History: Received January 24, 2017; Accepted April 11, 2017
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Abstract.  A numerical analysis capable of describing the early stage of a thermal microcavitation process in a water-rich biotissue without avalanche breakdown was developed. The analysis successfully reproduced the laser-induced heating, vapor bubble formation, bubble expansion, and shockwave propagation inside a water-rich biotissue during a thermal microcavitation process. Based on the analysis, it was determined that the evolution of the temperature, pressure, and laser-induced shockwave is dependent on the incident laser energy and laser pulse width. On the other hand, the early stage dynamics of the microcavitation process showed little dependence on the elastic modulus of the biotissue for the laser and tissue conditions studied.

Figures in this Article
© 2017 Society of Photo-Optical Instrumentation Engineers

Topics

Lasers ; Water ; Tissues

Citation

Sy-Bor Wen ; Kevin Ly ; Arun Bhaskar ; Morgan S. Schmidt and Robert J. Thomas
"Direct numerical simulation of the initial stage of a thermally induced microcavitation in a water-rich biotissue triggered by a nanosecond pulsed laser", J. Biomed. Opt. 22(5), 056002 (May 03, 2017). ; http://dx.doi.org/10.1117/1.JBO.22.5.056002


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