Research Papers: Imaging

Photothermal strain imaging

[+] Author Affiliations
Changhoon Choi, Joongho Ahn, Seungwan Jeon, Chulhong Kim

Pohang University of Science and Technology, Medical Device Innovation Center, Department of Creative IT Engineering, Pohang, Republic of Korea

J. Biomed. Opt. 22(7), 076005 (Jul 11, 2017). doi:10.1117/1.JBO.22.7.076005
History: Received February 8, 2017; Accepted June 19, 2017
Text Size: A A A

Abstract.  Vulnerable plaques are the major cause of cardiovascular disease, but they are difficult to detect with conventional intravascular imaging techniques. Techniques are needed to identify plaque vulnerability based on the presence of lipids in plaque. Thermal strain imaging (TSI) is an imaging technique based on ultrasound (US) wave propagation speed, which varies with the medium temperature. In TSI, the strain that occurs during tissue temperature change can be used for lipid detection because it has a different tendency depending on the type of tissue. Here, we demonstrate photothermal strain imaging (pTSI) using an intravascular ultrasound catheter. pTSI is performed by slightly and selectively heating lipid using a relatively inexpensive continuous laser source. We applied a speckle-tracking algorithm to US B-mode images for strain calculations. As a result, the strain produced in porcine fat was different from the strain produced in water-bearing gelatin phantom, which made it possible to distinguish the two. This suggests that pTSI could potentially be a way of differentiating lipids in coronary artery.

Figures in this Article
© 2017 Society of Photo-Optical Instrumentation Engineers

Citation

Changhoon Choi ; Joongho Ahn ; Seungwan Jeon and Chulhong Kim
"Photothermal strain imaging", J. Biomed. Opt. 22(7), 076005 (Jul 11, 2017). ; http://dx.doi.org/10.1117/1.JBO.22.7.076005


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement


 

  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.