Investigation of three-dimensional motion-free imaging of retinal diseases by Lissajous optical coherence tomography

Shuichi Makita; Masahiro Miura; Shinnosuke Azuma; Toshihiro Mino; Tatsuo Yamaguchi; Yoshiaki Yasuno

doi:10.1117/12.2608407

7 March 2022 Investigation of three-dimensional motion-free imaging of retinal diseases by Lissajous optical coherence tomography

Shuichi Makita, Masahiro Miura, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi, Yoshiaki Yasuno

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Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC119410P (2022) https://doi.org/10.1117/12.2608407
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Three-dimensional motion-free imaging of retinal diseases is investigated. The Lissajous scan with the 3-mm scan width is repeated during the gradually shifting center of the scanning pattern. The lateral and axial motion amounts are estimated by using image correlation of OCT and OCTA en face images and the OCT intensity cross-sections, respectively. It results in an imaging area of 6.8 mm or more in diameter. Several eyes with retinal diseases have been scanned. The three-dimensional OCT images are well reconstructed without significant motion artifacts. Although some eyes exhibit severe eye motion, the three-dimensional structure of the retina is well reconstructed.

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Shuichi Makita, Masahiro Miura, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi, and Yoshiaki Yasuno "Investigation of three-dimensional motion-free imaging of retinal diseases by Lissajous optical coherence tomography", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC119410P (7 March 2022); https://doi.org/10.1117/12.2608407

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KEYWORDS

Optical coherence tomography

3D image processing

Retinal scanning

Motion estimation

3D image reconstruction

In vivo imaging

Prototyping

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