Performance assessment of commercial continuous-wave near-infrared spectroscopy devices for the multi-center HEMOCOVID-19 clinical study

Lorenzo Cortese; Marta Zanoletti; Marco Pagliazzi; Umut Karadeniz; M. Atif Yaqub; David R. Busch; Jaume Mesquida; Turgut Durduran

doi:10.1117/12.2608215

7 March 2022 Performance assessment of commercial continuous-wave near-infrared spectroscopy devices for the multi-center HEMOCOVID-19 clinical study

Lorenzo Cortese, Marta Zanoletti, Marco Pagliazzi, Umut Karadeniz, M. Atif Yaqub, David R. Busch, Jaume Mesquida, Turgut Durduran

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Proceedings Volume PC11951, Design and Quality for Biomedical Technologies XV; PC119510C (2022) https://doi.org/10.1117/12.2608215
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

During the first peak of the COVID-19 pandemic, we have set up a clinical campaign in ten hospitals worldwide to assess the endothelial health of COVID-19 patients using commercial continuous-wave near-infrared spectroscopy (CW-NIRS) devices (PortaMon, Artinis, NL). In spite of the wide range of clinical applications, the reliability of common CW-NIRS systems for absolute oxygenation measurements was often questioned, opening issues of standardization. In addition, a multi-center trial itself opens issues about how to compare measurements performed by different operators, in different conditions and longitudinally over more than a year. Here, we present how we address these challenges by characterizing and comparing the performance of the devices, with phantom and in vivo experiments.

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Lorenzo Cortese, Marta Zanoletti, Marco Pagliazzi, Umut Karadeniz, M. Atif Yaqub, David R. Busch, Jaume Mesquida, and Turgut Durduran "Performance assessment of commercial continuous-wave near-infrared spectroscopy devices for the multi-center HEMOCOVID-19 clinical study", Proc. SPIE PC11951, Design and Quality for Biomedical Technologies XV, PC119510C (7 March 2022); https://doi.org/10.1117/12.2608215

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KEYWORDS

Continuous wave operation

Near infrared spectroscopy

Measurement devices

In vivo imaging

Medical devices

Oxygen

Reliability

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