Characterizing skin properties non-invasively by polarization-sensitive optical coherence tomography

Xin Zhou; Daniel C. Louie; Sina Maloufi; Yuheng Wang; Tim K. Lee; Shuo Tang

doi:10.1117/12.2649446

17 March 2023 Characterizing skin properties non-invasively by polarization-sensitive optical coherence tomography

Xin Zhou, Daniel C. Louie, Sina Maloufi, Yuheng Wang, Tim K. Lee, Shuo Tang

Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520S (2023) https://doi.org/10.1117/12.2649446
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) is a promising tool for non-invasive skin imaging, with its capability for depth-resolved, high-resolution, fast, and polarization-sensitive imaging. Thirty volunteers are recruited for skin imaging on the palm, arm, forehead, and eye corner. A segmentation algorithm based on intensity images will segment the epidermis and dermis layers and also stratum corneum if applicable. Multi-contrast images, including phase retardation, local birefringence, and degree of polarization uniformity, will be obtained from different skin layers. Possible relationships between the optical properties and skin features including layered structure, collagen organization, melanin concertation, and skin roughness will be investigated.

Conference Presentation

Citation Download Citation

Xin Zhou, Daniel C. Louie, Sina Maloufi, Yuheng Wang, Tim K. Lee, and Shuo Tang "Characterizing skin properties non-invasively by polarization-sensitive optical coherence tomography", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520S (17 March 2023); https://doi.org/10.1117/12.2649446

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KEYWORDS

Skin

Optical coherence tomography

Birefringence

Collagen

Image segmentation

Polarization

Surface roughness

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