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16 March 2023 Uncovering the long-term effects of mRNA COVID-19 vaccinations on platelets by high-speed optical imaging on a chip (Conference Presentation)
Yuqi Zhou, Masako Nishikawa, Hiroshi Kanno, Ruoxi Yang, Yuma Ibayashi, Ting-Hui Xiao, Walker Peterson, Maik Herbig, Nao Nitta, Shigeki Miyata, Yogendra Kanthi, Gustavo K. Rohde, Kyoji Moriya, Yutaka Yatomi, Keisuke Goda
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Proceedings Volume PC12390, High-Speed Biomedical Imaging and Spectroscopy VIII; PC123900P (2023) https://doi.org/10.1117/12.2655957
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
There is widespread concern about the safety of COVID-19 vaccinations related to platelet hyperactivity. However, their long-term influence on platelet activity remains unknown. We address this issue by applying a high-speed bright-field microscope based on optical frequency-division multiplexing and microfluidics for massive image-based analysis. We performed image-based single-cell profiling and temporal monitoring of circulating platelet aggregates in the blood samples of healthy human participants before and after they received three vaccination doses over a nearly one-year period. The results demonstrate no significant or persistent change in platelet activity after vaccine doses.
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© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Yuqi Zhou, Masako Nishikawa, Hiroshi Kanno, Ruoxi Yang, Yuma Ibayashi, Ting-Hui Xiao, Walker Peterson, Maik Herbig, Nao Nitta, Shigeki Miyata, Yogendra Kanthi, Gustavo K. Rohde, Kyoji Moriya, Yutaka Yatomi, and Keisuke Goda "Uncovering the long-term effects of mRNA COVID-19 vaccinations on platelets by high-speed optical imaging on a chip (Conference Presentation)", Proc. SPIE PC12390, High-Speed Biomedical Imaging and Spectroscopy VIII, PC123900P (16 March 2023); https://doi.org/10.1117/12.2655957
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KEYWORDS
Optical imaging
Profiling
Frequency division multiplexing
Human subjects
Image analysis
Microfluidics
Microscopes
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