Effect of small and large animal skull bone on photoacoustic signal

Qiuyun Xu; Bridget Volinski; Ali Hariri; Afreen Fatima; Mohammadreza Nasiriavanaki

doi:10.1117/12.2254183

23 March 2017 Effect of small and large animal skull bone on photoacoustic signal

Qiuyun Xu, Bridget Volinski, Ali Hariri, Afreen Fatima, Mohammadreza Nasiriavanaki

Proceedings Volume 10064, Photons Plus Ultrasound: Imaging and Sensing 2017; 100643S (2017) https://doi.org/10.1117/12.2254183
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Photoacoustic imaging (PAI) has proved to be a promising non-invasive technique for diagnosis, prognosis and treatment monitoring of neurological disorders in small and large animals. Skull bone effects both light illumination and ultrasound propagation. Hence, the PA signal is largely affected. This study aims to quantify and compare the attenuation of PA signal due to the skull obstacle in the light illumination path, in the ultrasound propagation path, or in both. The effect of mouse, rat, and mesocephalic dog skull bones, ex-vivo, is quantitatively studied.

Citation Download Citation

Qiuyun Xu, Bridget Volinski, Ali Hariri, Afreen Fatima, and Mohammadreza Nasiriavanaki "Effect of small and large animal skull bone on photoacoustic signal", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100643S (23 March 2017); https://doi.org/10.1117/12.2254183

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