Lab-based x-ray nanoCT imaging

Mark Müller; Sebastian Allner; Simone Ferstl; Martin Dierolf; Tomi Tuohimaa; Franz Pfeiffer

doi:10.1117/12.2254785

9 March 2017 Lab-based x-ray nanoCT imaging

Mark Müller, Sebastian Allner, Simone Ferstl, Martin Dierolf, Tomi Tuohimaa, Franz Pfeiffer

Proceedings Volume 10132, Medical Imaging 2017: Physics of Medical Imaging; 101320L (2017) https://doi.org/10.1117/12.2254785
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

Due to the recent development of transmission X-ray tubes with very small focal spot sizes, laboratory-based CT imaging with sub-micron resolutions is nowadays possible. We recently developed a novel X-ray nanoCT setup featuring a prototype nanofocus X-ray source and a single-photon counting detector. The system is based on mere geometrical magnification and can reach resolutions of 200 nm. To demonstrate the potential of the nanoCT system for biomedical applications we show high resolution nanoCT data of a small piece of human tooth comprising coronal dentin. The reconstructed CT data clearly visualize the dentin tubules within the tooth piece.

Citation Download Citation

Mark Müller, Sebastian Allner, Simone Ferstl, Martin Dierolf, Tomi Tuohimaa, and Franz Pfeiffer "Lab-based x-ray nanoCT imaging", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101320L (9 March 2017); https://doi.org/10.1117/12.2254785

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