Mie scattering characterization by ultra-spectral illumination using micro-sized tunable liquid crystal optical filters (Conference Presentation)

Fartash Vasefi; Russell Barbour; Caleb Stoltzfus; Zeb Barber; Daniel Farkas

doi:10.1117/12.2292620

11 June 2018 Mie scattering characterization by ultra-spectral illumination using micro-sized tunable liquid crystal optical filters (Conference Presentation)

Fartash Vasefi, Russell Barbour, Caleb Stoltzfus, Zeb Barber, Daniel Farkas

Author Affiliations +

Proceedings Volume 10497, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI; 104971D (2018) https://doi.org/10.1117/12.2292620
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

We developed a confocal microscope and ultra-spectral light source containing Liquid Crystal Arrayed Microcavities (LCAM) as a new technology for controlled ultra-narrow optical filtering (FWHM ∼0.1 nm). LCAMs use picoliter volume Fabry–Perot-type optical cavities filled with liquid crystal for wavelength tuning. With sub-nanometer spectral resolution, we measured spectral resonance from scattering particles to validate the measurements with simulation results. We measured chicken liver and breast muscle, pig skin and muscle and compared with results from literature. The main application is the estimation of nuclear size in biological tissues for noninvasive assessment equivalent to histopathology.

Conference Presentation

Citation Download Citation

Fartash Vasefi, Russell Barbour, Caleb Stoltzfus, Zeb Barber, and Daniel Farkas "Mie scattering characterization by ultra-spectral illumination using micro-sized tunable liquid crystal optical filters (Conference Presentation)", Proc. SPIE 10497, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI, 104971D (11 June 2018); https://doi.org/10.1117/12.2292620

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available