RGB camera-based functional imaging of in vivo biological tissues

Izumi Nishidate; Satoko Kawauchi; Shunichi Sato; Manabu Sato; Yoshihisa Aizu; Yasuaki Kokubo

doi:10.1117/12.2513306

5 November 2018 RGB camera-based functional imaging of in vivo biological tissues

Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yoshihisa Aizu, Yasuaki Kokubo

Proceedings Volume 10815, Optical Design and Testing VIII; 108150S (2018) https://doi.org/10.1117/12.2513306
Event: SPIE/COS Photonics Asia, 2018, Beijing, China

Abstract

We investigated a rapid imaging method to monitor the spatial distribution of total hemoglobin concentration (C_HbT), the tissue oxygen saturation (StO₂), and the scattering power b in the expression of musp=a(lambda)^-b as the scattering parameters in cerebral cortex using a digital red-green-blue camera. In the method, Monte Carlo simulation (MCS) for light transport in brain tissue is used to specify a relation among the RGB-values and the concentration of oxygenated hemoglobin (C_HbO), that of deoxygenated hemoglobin (C_HbR), and the scattering power b. The results in this study indicate potential of the method to evaluate the physiology and loss of tissue viability in biological tissues.

Citation Download Citation

Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yoshihisa Aizu, and Yasuaki Kokubo "RGB camera-based functional imaging of in vivo biological tissues", Proc. SPIE 10815, Optical Design and Testing VIII, 108150S (5 November 2018); https://doi.org/10.1117/12.2513306

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