Sensitivity analysis of a multibranched light guide for real time hyperspectral imaging systems

Craig M. Browning; Samuel Mayes; Joshua Deal; Arslan Arshad; Samantha Gunn Mayes; Marina Parker; Thomas C. Rich; Silas J. Leavesley

doi:10.1117/12.2510506

27 February 2019 Sensitivity analysis of a multibranched light guide for real time hyperspectral imaging systems

Craig M. Browning, Samuel Mayes, Joshua Deal, Arslan Arshad, Samantha Gunn Mayes, Marina Parker, Thomas C. Rich, Silas J. Leavesley

Author Affiliations +

Proceedings Volume 10871, Multimodal Biomedical Imaging XIV; 1087107 (2019) https://doi.org/10.1117/12.2510506
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Hyperspectral imaging (HSI) is a spectroscopic technique which captures images at a high contrast over a wide range of wavelengths to show pixel specific composition. Traditional uses of HSI include: satellite imagery, food distribution quality control and digital archaeological reconstruction. Our lab has focused on developing applications of HSI fluorescence imaging systems to study molecule-specific detection for rapid cell signaling events or real-time endoscopic screening. Previously, we have developed a prototype spectral light source, using our modified imaging technique, excitationscanning hyperspectral imaging (HIFEX), coupled to a commercial colonoscope for feasibility testing. The 16 wavelength LED array was combined, using a multi-branched solid light guide, to couple to the scope’s optical input. The prototype acquired a spectral scan at near video-rate speeds (~8 fps). The prototype could operate at very rapid wavelength switch speeds, limited to the on/off rates of the LEDs (~10 μs), but imaging speed was limited due to optical transmission losses (~98%) through the solid light guide. Here we present a continuation of our previous work in performing an in-depth analysis of the solid light guide to optimize the optical intensity throughput. The parameters evaluated include: LED intensity input, geometry (branch curvature and combination) and light propagation using outer claddings. Simulations were conducted using a Monte Carlo ray tracing software (TracePro). Results show that transmission within the branched light guide may be optimized through LED focusing lenses, bend radii and smooth tangential branch merges. Future work will test a new fabricated light guide from the optimized model framework.

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Craig M. Browning, Samuel Mayes, Joshua Deal, Arslan Arshad, Samantha Gunn Mayes, Marina Parker, Thomas C. Rich, and Silas J. Leavesley "Sensitivity analysis of a multibranched light guide for real time hyperspectral imaging systems", Proc. SPIE 10871, Multimodal Biomedical Imaging XIV, 1087107 (27 February 2019); https://doi.org/10.1117/12.2510506

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KEYWORDS

Light emitting diodes

Waveguides

Solids

Prototyping

Endoscopy

Hyperspectral imaging

Data modeling

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