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14 August 2019 The role of PDT in nasopharyngeal cancer in Indonesia (Conference Presentation)
Bing Tan
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Proceedings Volume 11070, 17th International Photodynamic Association World Congress; 1107052 (2019) https://doi.org/10.1117/12.2527759
Event: 17th International Photodynamic Association World Congress, 2019, Cambridge, Massachusetts, United States
Abstract
The role of PDT in nasopharyngeal cancer in Indonesia I.B. Tan NPC is a rare disease in the Western world, but is endemic in certain parts of south East Asia and China. The last decades the outcome of the treatment has improved considerable. Concurrent chemo-radiation has become the treatment of choice in advanced NPC. Five years survival figures of 80-90% for T1-T2 and 60-80% for T3-T4 are not exceptional. However, figures in low income countries are less favorable. Under capacity of radiotherapy units and poor compliance to treatment are the main concerns. A study in a tertiary university hospital in Yogyakarta Indonesia showed 3yrs survival of 30% with many patients with residual disease. Photo Dynamic Therapy (PDT) has been shown to be effective in residual and recurrent nasopharyngeal cancer with 3 year survival rates of over 65%. It’s noninvasive and only limited infra-structure is needed. Future research should focus on innovative treatment strategies like immunotherapy in combination with PDT as an induction therapy to reduce the tumor load during the waiting time.
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Bing Tan "The role of PDT in nasopharyngeal cancer in Indonesia (Conference Presentation)", Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 1107052 (14 August 2019); https://doi.org/10.1117/12.2527759
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KEYWORDS
Photodynamic therapy
Cancer
Radiotherapy
Tumors
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