Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments

Anurag Behera; Laura Di Sieno; Sumeet Rohilla; Antonio Pifferi; Alessandro Torricelli; Davide Contini; Benedikt Krämer; Felix Koberling; Alberto Dalla Mora

doi:10.1117/12.2526792

11 July 2019 Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments

Anurag Behera, Laura Di Sieno, Sumeet Rohilla, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Benedikt Krämer, Felix Koberling, Alberto Dalla Mora

Author Affiliations +

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 1107402 (2019) https://doi.org/10.1117/12.2526792
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

We present here a novel time-domain diffuse optical detection chain consisting of a large area Silicon PhotoMultipliers (SiPM) coupled to a high count-rate timing electronics (TimeHarp 260 PICO) to achieve sustainable count-rates up to 10 Mcps without significant distortions to the distribution of time-of-flight (DTOF). Thanks to the large area of the detector (9 mm²) and the possibility to directly place it in contact with the sample (thus achieving a numerical aperture close to unity), the photon collection efficiency of the proposed detection chain is almost two orders of magnitude higher than traditional fiber-mounted PMT-based systems. This allows the detection also of the few late photons coming from deeper layers at short acquisition times, thus improving the robustness of the detection of localized inhomogeneities. We then demonstrate that, despite the high dark count rate of the detector, it is possible to reliably extract the optical properties of calibrated phantoms, with proper linearity and accuracy. We also explore the capability of the new detection chain for detecting brain activations. This work opens up the possibility of ultimate performance in terms of high signal and photon throughput, with compact, low cost, relatively simple front-end electronics detector coupled to innovative timing electronics, with exciting opportunities to expand it to tomographic applications.

Citation Download Citation

Anurag Behera, Laura Di Sieno, Sumeet Rohilla, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Benedikt Krämer, Felix Koberling, and Alberto Dalla Mora "Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107402 (11 July 2019); https://doi.org/10.1117/12.2526792

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
4 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Electronics

Sensors

Absorption

Optical properties

Scattering

In vivo imaging

Picosecond phenomena

Show All Keywords

Keywords/Phrases

Search In:

Publication Years