CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11228 > Article
Presentation
9 March 2020 Quantitative three-dimensional collagen fiber modeling from spectral domain optical coherence tomography (OCT) images (Conference Presentation)
James P. McLean, Shuyang Fang, Kristin M. Myers, Christine P. Hendon
Author Affiliations +
Proceedings Volume 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV; 112280Z (2020) https://doi.org/10.1117/12.2549102
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
An image processing method was developed for automatically generating three-dimensional models of human uterine collagen fiber networks from spectral-domain optical coherence tomography (SD-OCT) images. A novel image processing scheme was used to segment the tissue from the image volume and divide it into “processing regions” that adapt to the tissue topology. Quantitative fiber analysis was performed on b-scan and en-face image patches, enabled by a custom b-scan preprocessing pipeline. Three-dimensional fiber architecture was analyzed in over 100 mosaic volumes from five different patients (2 pregnant, 3 non-pregnant), revealing a highly complex and patient-specific network of fibrous collagen and myocyte bundles.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
James P. McLean, Shuyang Fang, Kristin M. Myers, and Christine P. Hendon "Quantitative three-dimensional collagen fiber modeling from spectral domain optical coherence tomography (OCT) images (Conference Presentation)", Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280Z (9 March 2020); https://doi.org/10.1117/12.2549102
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
3D modeling
Optical coherence tomography
3D image processing
Collagen
Tissues
Image processing
Spectral models
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top