Spectropolarimetry diagnostics of cervical cytological smears for availability of papillomavirus

Olexander Peresunko; Sergey Yermolenko; Nina Horodynska

doi:10.1117/12.2568384

21 August 2020 Spectropolarimetry diagnostics of cervical cytological smears for availability of papillomavirus

Olexander Peresunko, Sergey Yermolenko, Nina Horodynska

Proceedings Volume 11510, Applications of Digital Image Processing XLIII; 115102K (2020) https://doi.org/10.1117/12.2568384
Event: SPIE Optical Engineering + Applications, 2020, Online Only

Conference Poster

Abstract

The purpose of the work was to demonstrate the possibility of optical diagnosis of cytological smears of the cervix for the presence of HPV using spectral and polarization methods. Comparison of cervical specimens with and without coilocytosis, irradiated with a range-shifted polarized radiation, showed significant differences in the values of linear dichroism and its spectral dependences. The difference between the coilocyte response characteristic in the range 395-415 nm was calculated using computer programs. As a result, the use of spectropolarization studies and the fluorescence method will improve the accuracy of patient selection for a costly procedure - high-carcinogenic DNA diagnostics of HPV by the standard method of polymerase chain reaction.

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Olexander Peresunko, Sergey Yermolenko, and Nina Horodynska "Spectropolarimetry diagnostics of cervical cytological smears for availability of papillomavirus", Proc. SPIE 11510, Applications of Digital Image Processing XLIII, 115102K (21 August 2020); https://doi.org/10.1117/12.2568384

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