High-pressure microscopy for manipulating bionanomachines in living cells

Masayoshi Nishiyama

doi:10.1117/12.2573533

15 June 2020 High-pressure microscopy for manipulating bionanomachines in living cells

Masayoshi Nishiyama

Proceedings Volume 11522, Optical Manipulation and Structured Materials Conference 2020; 1152216 (2020) https://doi.org/10.1117/12.2573533
Event: SPIE Technologies and Applications of Structured Light, 2020, Yokohama, Japan

Abstract

High-pressure microscopy is one of the powerful techniques that manipulate molecular machines working in cells. We successfully developed a new high-pressure microscope that is optimized both for the best image formation and for stability under high hydrostatic pressure. The techniques described here could be extended to study various biological samples, including molecules, cells and individuals.

Citation Download Citation

Masayoshi Nishiyama "High-pressure microscopy for manipulating bionanomachines in living cells", Proc. SPIE 11522, Optical Manipulation and Structured Materials Conference 2020, 1152216 (15 June 2020); https://doi.org/10.1117/12.2573533

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