Multimodal imaging platform for image-guided surgery: application to blood perfusion assessment

Silvère Ségaud; Enagnon Aguénounon; Joseph Angelo; Sara Gravelyn; Henrique Waxin; Lucile Zorn; Julien Lamy; Murielle Torregrossa; Michele Diana M.D.; Sylvain Lecler; Sylvain Gioux

doi:10.1117/12.2578461

5 March 2021 Multimodal imaging platform for image-guided surgery: application to blood perfusion assessment

Silvère Ségaud, Enagnon Aguénounon, Joseph Angelo, Sara Gravelyn, Henrique Waxin, Lucile Zorn, Julien Lamy, Murielle Torregrossa, Michele Diana M.D., Sylvain Lecler, Sylvain Gioux

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Proceedings Volume 11634, Multimodal Biomedical Imaging XVI; 116340J (2021) https://doi.org/10.1117/12.2578461
Event: SPIE BiOS, 2021, Online Only

Abstract

Despite the technological evolutions that transform the operating rooms nowadays, a major clinical need remains: surgeons need to distinguish healthy from diseased tissues while performing a procedure. Tissue status assessment procedures such as blood perfusion monitoring require objective input that can potentially be obtained with fluorescence imaging and oxygenation imaging. We developed a multimodal imaging platform for performing widefield quantitative oxygenation imaging and fluorescence imaging in a clinical environment. We demonstrate in-vivo the impact of widefield quantitative oxygenation imaging on blood perfusion assessment. Fluorescence imaging provided by the system is used in complement to confirm the outcome of oxygenation imaging.

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Silvère Ségaud, Enagnon Aguénounon, Joseph Angelo, Sara Gravelyn, Henrique Waxin, Lucile Zorn, Julien Lamy, Murielle Torregrossa, Michele Diana M.D., Sylvain Lecler, and Sylvain Gioux "Multimodal imaging platform for image-guided surgery: application to blood perfusion assessment", Proc. SPIE 11634, Multimodal Biomedical Imaging XVI, 116340J (5 March 2021); https://doi.org/10.1117/12.2578461

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KEYWORDS

Blood

Luminescence

Multimodal imaging

Image-guided intervention

Tissues

Imaging systems

Near infrared

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